Excessively high soluble Klotho in patients with acromegaly
Journal of Internal Medicine, 07/11/2012
Sze L et al. – This is the first study to show dramatically increased soluble Klotho levels in an acquired disease in humans. Reversal following tumour removal suggests a causal relation between the growth hormone (GH)–producing adenoma and high serum Klotho concentration in acromegaly.