Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 4. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease 5. Rapid correction of low vitamin D status in nursing home residents
Top Ten Searches
etanercept hypertension chf antiphospholipid fibrosis mrsa scid renal cell rickets counterpulsationYour Article Summary
Differences in long-term disease activity and treatment of adult patients with childhood- and adult-onset systemic lupus erythematosus
Arthritis Care and Research , 01/05/09
Hersh AO et al. – Study demonstrates important differences in the outcomes of patients with childhood systemic lupus erythematosus (cSLE) and adult SLE (aSLE), and provides important prognostic information about long-term SLE disease activity and treatment.
Methods- Aim was to compare differences in long-term outcome cSLE and aSLE
- Data derived from a cohort of 885 adult subjects with SLE (90 cSLE, 795 aSLE)
- Baseline and 1-yr f/u data obtained via structured 1-hr telephone interviews
- Differences in organ involvement and disease morbidity, current disease status and activity, past and current medication use, and number of physician visits were compared
- Average disease duration for cSLE and aSLE subgroups was 16.5 and 13.4 yrs, respectively
- Mean age at f/u was 30.5 and 49.9 yrs, respectively
- cSLE subjects had a higher frequency of SLE-related renal disease, whereas aSLE subjects were more likely to report a history of pulmonary disease
- Rates of clotting disorders, seizures, and myocardial infarction were similar between the 2 groups
- At f/u, cSLE subjects had lower overall disease activity, but were more likely to be taking steroids and other immunosuppressive therapies
- Total number of yearly physician visits was similar between the 2 groups, although cSLE subjects had a higher number of nephrology visits
Related Articles
Citrulline dependence of anti-cyclic citrullinated peptide antibodies in systemic lupus erythematosus as a marker of deforming/erosive arthritis
Journal of Rheumatology, 11/06/09
Relevance Score: 94%
Interferon-gamma gene polymorphisms associated with susceptibility to systemic lupus erythematosus
Annals of Rheumatic Diseases, 11/23/09
Relevance Score: 92%
The relationship between race, cigarette smoking and carotid intimal medial thickness in systemic lupus erythematosus
Lupus, 11/30/09
Relevance Score: 91%
Analysis of correlations between selected endothelial cell activation markers, disease activity, and nailfold capillaroscopy microvascular changes in SLE patients
Clinical Rheumatology, 11/17/09
Relevance Score: 90%
B lymphocyte stimulator expression in pediatric systemic lupus erythematosus and juvenile idiopathic arthritis patients
Arthritis & Rheumatism, 11/04/09
Relevance Score: 90%
Today in Orthopedic/Physical Med...keeping you current
Receive free subspecialty "5-minute updates" via email
Elevated Circulating and Synovial Fluid Endoglin Are Associated with Primary Knee Osteoarthritis Severity
Archives of Medical Research, 12/20/09
Effects of Aerobic Conditioning on Salivary IgA and Plasma IgA, IgG and IgM in Older Men and Women
International Journal of Sports Medicine, 12/19/09
Stength, Endurance or Combined Training Elicit Diverse Skeletal Muscle Myosin Heavy Chain Isoform Proportion but Unaltered Androgen Receptor Concentration in Older Men
International Journal of Sports Medicine, 12/19/09
Sponsor
Article Search
Sponsor
Sponsor


See Latest Articles


