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Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase
Journal of Clinical Investigation, 04/23/07
Shotaro Iwamoto, et al. - Because of their low asparagine synthetase (ASNS) expression and asparagine biosynthesis, acute lymphoblastic leukemia (ALL) cells are exquisitely sensitive to asparagine depletion. Consequently, asparaginase is a major component of ALL therapy, but the mechanisms regulating the susceptibility of leukemic cells to this agent are unclear
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Risk of dying from prostate cancer in men randomized to screening
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Update on oral lichen planus
Expert Review of Dermatology, 10/14/09
Oestrogen plus progestin and lung cancer in postmenopausal women (Womens Health Initiative trial): a post-hoc analysis of a randomised controlled trial
The Lancet, 10/12/09
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