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Thiazolidinediones and vascular damage
Current Opinion in Endocrinology, Diabetes and Obesity, 03/05/07

Goldberg, Ronald B, - Will use of these drugs prevent cardiovascular disease?
>Summary: The purpose of this review was to investigate the possibility of thiazolidinedione agents having vasculoprotective effects and if so whether these are associated with the prevention of cardiovascular disease.
Outcomes: The weight of the experimental, subclinical and clinical assessments of the effects of these agents supports the contention that they are vasculoprotective. In the final analysis their use in clinical practice to prevent cardiovascular disease will mostly depend on whether clinical trials consistently demonstrate that they reduced cardiovascular events

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