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Dual Endothelin Receptor Blockade Acutely Improves Insulin Sensitivity in Obese Patients With Insulin Resistance and Coronary Artery Disease
Diabetes Care, 03/05/07
Gunvor Ahlborg, MD, PHD., et al. – Endothelin (ET)-1 is a vasoconstrictor and proinflammatory peptide that may inhibit glucose uptake. The objective of the study was to investigate if ET (selective ETA and dual ETA+ETB) receptor blockade improves insulin sensitivity in patients with insulin resistance and coronary artery disease...Conclusion: Dual ETA+ETB receptor blockade acutely enhances insulin sensitivity in patients with insulin resistance and coronary artery disease, indicating an important role for endogenous ET-1
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Today in Atherosclerosis/Lipids...keeping you current
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Lipid-altering efficacy and safety of ezetimibe/simvastatin versus atorvastatin in patients with hypercholesterolemia and the metabolic syndrome (from the VYMET study)
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Today in Clinical Pharmacology...keeping you current
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Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: A systematic review
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Today in Endocrinology...keeping you current
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The Lancet, 06/23/09
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