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Serum Zinc Level and Coronary Heart Disease Events in Patients With Type 2 Diabetes
Diabetes Care, 03/05/07
Soinio, M., et al. – Low serum zinc level a risk factor for CHD events in this diabetic population.
>Summary: Serum zinc values were obtained from a group of 1,059 patients with type 2 diabetes, aged 45 - 64 years. Mean duration of diabetes was 8 years. CHD mortality and the incidence of nonfatal MI were assessed in a 7-year follow-up.
Outcomes: Patients with a serum zinc concentration of lower 14.1 µmol/l at baseline had a higher risk for death from CHD than patients with serum zinc level above 14.1 µmol/l. The risks for fatal or nonfatal MI were 30.5 and 22.0%, respectively. A Cox regression analyses determined that low serum zinc concentration was significantly associated with CHD mortality and all CHD events even after adjustment for confounding variables
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