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Consistently Stable or Decreased Body Mass Index in Young Adulthood and Longitudinal Changes in Metabolic Syndrome Components: The Coronary Artery Risk Development in Young Adults Study
Circulation, 03/02/07

Lloyd-Jones, Donald M. MD, ScM., et al. – Is BMI the key to halting the the progression of metabolic syndrome risk factors with advancing age?
>Summary: Prospective study of 1358 men and 1321 women ages 18 to 30 years enrolled in from 1985 to 1986, were stratified into groups by baseline BMI and change in BMI Patients were monitored for changes in metabolic syndrome components over 15 years.
Outcomes: Over 15 years, participants whose BMI remained stable BMI had essentially unchanged levels of metabolic syndrome components, regardless of their baseline BMI, whereas those with an increased BMI had progressively worsening levels. The incidence of metabolic syndrome at year 15 was was lower at 2.2% in the stable BMI group versus 18.8% in the group whose BMI increased. The incidence of developing metabolic syndrome with advancing age can be decreased by maintaining a stable BMI over time