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The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin
Journal of Lipid Research, 03/02/07
Dawn E. Telford, et al. – The combination of ezetimibe, an inhibitor of Niemann-Pick C1-like 1 protein (NPC1L1), and an HMG-CoA reductase inhibitor decreases cholesterol absorption and synthesis. In clinical trials, ezetimibe plus simvastatin produces greater LDL-cholesterol reductions than does monotherapy. The molecular mechanism for this enhanced efficacy has not been defined
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Today in Atherosclerosis/Lipids...keeping you current
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Non-soy legume consumption lowers cholesterol levels: A meta-analysis of randomized controlled trials
Nutrition, Metabolism & Cardiovascular Diseases, 12/07/09
Endothelial activation, inflammation and premature atherosclerosis in children with familial dyslipidemia
Atherosclerosis, 12/07/09
Altered composition of triglyceride-rich lipoproteins and coronary artery disease in a large case–control study
Atherosclerosis, 12/07/09
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Associations of genetic polymorphisms of arachidonate 5-lipoxygenase-activating protein with risk of coronary artery disease in a European–American population
Atherosclerosis, 12/07/09
Qualitative assessment of previous evidence and an updated meta-analysis confirms lack of association between the ESR1 rs2234693 (PvuII) variant and coronary heart disease in men and women
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Salt intake, stroke, and cardiovascular disease: meta-analysis of prospective studies
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Today in Clinical Pharmacology...keeping you current
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Linezolid in the Treatment of Multidrug-Resistant Tuberculosis
Clinical Infectious Diseases, 12/07/09
Review: erythropoiesis-stimulating agents increase mortality in patients with cancer
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MLN3897 plus methotrexate in patients with rheumatoid arthritis: Safety, efficacy, pharmacokinetics, and pharmacodynamics of an oral CCR1 antagonist in a phase IIa, double-blind, placebo-controlled, randomized, proof-of-concept study
Arthritis & Rheumatism, 12/07/09
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