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See Latest ArticlesRituximab in the treatment of autoimmune haematological disorders
British Journal of Haematology, 04/10/08
Garvey B - In a review of data supporting the use of rituximab in 4 key autoimmune haematological disorders: idiopathic thrombocytopenic purpura (ITP); autoimmune haemolytic anaemia (AIHA); acquired haemophilia; and thrombotic thrombocytopenic purpura (TTP), these data suggest that rituximab provides an effective and well-tolerated alternative treatment option for these pts, many of whom have limited treatment choices
Methods- It has become clear that B cells play a key role in both the development and perpetuation of autoimmunity, suggesting that B-cell depletion could be a valuable treatment approach for pts with autoimmune diseases
- This article reviews data supporting the use of rituximab in 4 key autoimmune haematological disorders
- Although treatment of ITP, AIHA, acquired haemophilia, and TTP with rituximab is still relatively uncommon, results indicate that pts of all ages can respond to rituximab, irrespective of the number or type of prior treatments received
- Pts with these diseases receiving rituximab experienced predominantly mild adverse events, with only a few serious adverse events reported
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Today in Hematology/Oncology...keeping you current
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Cancer epidemiology in France in 2010, comparison with the USA
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