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Beta2 glycoprotein I (beta2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome
Blood, 10/09/09
Sikara MP et al. – This study makes evident that beta2GPI forms stable complexes with PF4, leading to the stabilization of beta2GPI dimeric structure which facilitates the antibody recognition. This interaction can probably be involved in the precoagulant tendency of APS.
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