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See Latest ArticlesReduced immunoglobulin class switch recombination in the absence of Artemis
Blood, 08/24/09
Rivera–Munoz P et al. – Significant increase in DNA microhomology usage is the signature of CSR junctions obtained from human RS–SCID patients harboring hypomorphic Artemis mutations. Altogether this indicates that Artemis participates in the repair of a subset of DNA breaks generated during CSR.
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ARTEMIS Nuclease Facilitates Apoptotic Chromatin Cleavage
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