Top renal cell Articles in Internal Medicine

Effect of Collecting Duct Histology on Renal Cell Cancer Outcome
The Journal of Urology, 11/18/2009

Wright JL et al. – Compared to patients with clear cell renal cell carcinoma those with collecting duct renal cell carcinoma have higher stage and are more often black. Even after adjusting for demographic, surgical and ... is significantly worse in patients with collecting duct rather than clear cell renal cell carcinoma. [more...]

The Expression of Thrombospondin-1 and p53 in Clear Cell Renal Cell Carcinoma: Its Relationship to Angiogenesis, Cell Proliferation and Cancer Specific Survival
The Journal of Urology, 10/14/2009

Zubac DP et al. – Thrombospondin–1 expression is strongly associated with prognostic tumor features in clear cell renal cell carcinoma and is an independent ... density and thrombospondin–1 expression, and indicate that thrombospondin–1 may have an impact on angiogenesis, proliferation and tumor aggressiveness in clear cell renal cell carcinoma. [more...]

Multidisciplinary treatment including sorafenib stabilized the bone metastases of renal cell carcinoma in an immunosuppressed renal transplant recipient
International Journal of Clinical Oncology, 10/30/2009

Hasegawa Y et al. – The authors report a case of metastatic renal cell carcinoma in the native kidney of a renal transplant recipient. Subsequent administration of ... 18 months after nephrectomy. This is the first reported case of sorafenib administration to a renal transplant recipient with metastatic renal cell carcinoma. [more...]

Chromosomal abnormalities of clear cell renal cell carcinoma: Frequent gain of chromosome 7
Pathology International, 11/19/2009

Kuroda N et al. – The present study shows that gain of chromosome 7 is not exclusive to papillary RCC, but it can be found in clear cell RCC as well, and this finding may represent a diagnostic pitfall in distinguishing clear cell RCC ... from papillary RCC. [more...]

Prognostic Value of Capsular Invasion for Localized Clear-Cell Renal Cell Carcinoma
European Urology, 11/10/2009

Cho HJ et al. – Capsular invasion in clear–cell renal cell carcinoma is associated with specific clinicopathologic findings and has an impact on prognosis in localized tumors. [more...]

Simultaneous Infiltration of Polyfunctional Effector and Suppressor T Cells into Renal Cell Carcinomas
Cancer Research, 11/03/2009

Attig S et al. – Compared with the same patient's peripheral blood, T lymphocytes present inside tumors were found to be enriched in functional CD4+ cells of the Th1 lineage and in effector memory CD8+ cells. Additionally, several ... regulatory T cells were identified that may synergize to locally dampen antitumor T–cell responses. [more...]

Prognostic factors for renal cell carcinoma: Trakya University experience from Turkey
European Journal of Cancer Care, 10/22/2009

Yurut–Caloglu V et al. – The purpose of the present study is to evaluate the prognostic factors of patients with renal cell carcinoma. The authors concluded that the most important prognostic factors for patients with renal ... cell carcinomas are ECOG performance status, tumour size and lymphatic invasion. [more...]

Strong expression of chemokine receptor CXCR4 by renal cell carcinoma cells correlates with metastasis
Clinical and Experimental Metastasis, 11/02/2009

Wang L et al. – Renal cell carcinoma metastasis was associated with higher expression of CXCR4 and interaction of CXCR4 and its ligand CXCL12 resulted in the internalization of CXCR4 from ... the CXCR4–CXCL12 axis in the metastasis of renal cell carcinoma. [more...]

Multipotent mesenchymal stromal cell therapy in renal disease and kidney transplantation
Nephrology Dialysis Transplantation, 11/05/2009

Reinders MEJ et al. – Multipotent mesenchymal stromal cells (MSCs), often referred to as mesenchymal stem cells, are of particular interest as a cell therapy model, as this is one of the few cell types that are on ... different areas of application. Evidence for the renoprotective mechanisms of MSCs as well as their therapeutic possibilities and potential hazards in acute and chronic renal disease and allograft rejection is summarized. [more...]

Prognostic Impact of Histological Subtype on Surgically Treated Localized Renal Cell Carcinoma
The Journal of Urology, 10/12/2009

Teloken PE et al. – Clear cell histology seems to be independently associated with worse outcomes in patients who undergo surgery for renal cell carcinoma even after controlling for widely accepted factors influencing prognosis. [more...]