Top hypertension Articles in Internal Medicine

Effective strategies for management of hypertension after vascular endothelial growth factor signaling inhibition therapy: Results from a phase II randomized, factorial, double-blind study of cediranib in patients with advanced solid tumors
Journal of Clinical Oncology, 11/13/2009

Langenberg MHG et al. – All four regimens were well ... The current cediranib hypertension management protocol appears to be effective in managing hypertension compared with previous cediranib studies where no plan was in place, and early recognition and treatment of hypertension is likely to reduce the number of severe hypertension events. This protocol ... cediranib 30 or 45 mg/d with or without antihypertensive prophylaxis All patients developing hypertension on cediranib treatment treated with standardized, predefined hypertension management protocol Results Cediranib generally well tolerated, and all groups ... or interruptions Increases in blood pressure, including moderate and severe readings of hypertension, seen early in treatment in all groups and successfully managed Severe hypertension occurred in 1 patient receiving prophylaxis versus 18 in nonprophylaxis groups 9 partial [more...]

Hypertension treatment and management concerns in the elderly
Aging Health, 10/07/2009

Fischer MJ – Hypertension is a common condition that increases steadily with age and is most prevalent in the elderly. In the last two decades, a number of clinical trials have increased the awareness of the consequences of ... hypertension and enhanced the understanding of its treatment. Both pharmacologic and nonpharmacologic strategies have been found to be successful in treating hypertension and reducing the frequency of associated morbidity and mortality in the elderly. Moreover, these treatments appear to be well ... tolerated and feasible to implement in geriatric populations. It is incumbent upon healthcare providers and policymakers alike to diligently pursue judicious management of hypertension in older patients. [more...]

Practical strategies for management of hypertension in the elderly
Internet Source, 10/13/2009

The elderly are the fastest–growing population with the highest prevalence of hypertension. The major factors contributing to poor blood pressure control include inadequate intensity of treatment, suboptimal drug regimens, high prevalence of resistant hypertension ... changes, and higher prevalence of concomitant metabolic and cardiovascular complications in older persons. Key strategies for hypertension treatment in elderly include lifestyle changes and hypertension treatment until target BP goal is reached with mono or combination therapy. [more...]

Hypertension in Women: More Evidence for the Role of Lifestyle
Nursing for Women's Health, 10/12/2009

Hellwig JP – The association between combinations of three (normal BMI, daily vigorous exercise, and DASH–style diet), four (three low–risk factors plus modest alcohol intake), five (four low–risk factors plus ... risk factors and the risk of developing hypertension was analyzed. During the follow–up, a total of 12,319 new cases of hypertension were reported. All six modifiable risk factors were independently associated with the risk of developing hypertension during follow–up after also adjusting ... hypertension, smoking status and use of oral contraceptives. For women who had all six low–risk factors (0.3 percent of the population), they had about an 80 percent lower risk of developing hypertension. [more...]

Intradialytic Hypertension: A Less-Recognized Cardiovascular Complication of Hemodialysis
American Journal of Kidney Diseases, 10/28/2009

Inrig JK – Although intradialytic hypertension often is underappreciated, recent studies suggest that it should not be ignored. However, further work is necessary to elucidate the pathophysiologic ... intradialytic hypertension and its appropriate management and determine whether treatment of intradialytic hypertension can improve clinical outcomes. [more...]

Retinal arteriolar narrowing increases the likelihood of chronic kidney disease in hypertension
Journal of Hypertension, 10/26/2009

Sabanayagam C et al. – The findings show that the presence of microvascular disease in the retina increases the likelihood of CKD associated with hypertension and suggest that examination of the retinal vasculature may aid in stratification of CKD risk in hypertensive ... nephrology/urology,hypertension,general medicine [more...]

Carotid artery atherosclerosis in hypertensive patients with a functional LDL receptor-related protein 6 gene variant
Nutrition, Metabolism & Cardiovascular Diseases, 10/20/2009

Sarzani R et al. – Beside the role of established risk factors, 1062V variant of LRP6 and CAA are strongly associated in hypertensive patients, making LRP6 a novel relevant ... in the presence of hypertension. [more...]

Secondary Hypertension in Overweight and Stage 1 Hypertensive Children: A Midwest Pediatric Nephrology Consortium Report
The Journal of Clinical Hypertension, 10/12/2009

Kapur G et al. – The study revealed no significant differences in the mean age at diagnosis, distribution of overweight, and stage 1 or 2 hypertensive children between PH ... Overweight and presence of stage 1 hypertension should not preclude evaluation for SH. [more...]

Advancing the Prevention and Control of Hypertension
American Journal of Lifestyle Medicine, 11/16/2009

Terre L – Hypertension is on a worrisome public health trajectory. This review discusses some key contributing dynamics as well as considerations for progress toward the prevention and control of hypertension and its comorbidities. [more...]

Sex-specific hemodynamic and non-hemodynamic determinants of aortic root size in hypertensive subjects with left ventricular hypertrophy
Hypertension Research, 11/09/2009

Cipolli JAA et al. – The results suggest that both volume overload and abdominal obesity are related to AoR dilatation in hypertensive women, whereas AoR enlargement is associated more ... related parameters in hypertensive men with LV hypertrophy. [more...]