Top mrsa Articles in Infectious Disease

Implementation of a methicillin-resistant Staphylococcus aureus (MRSA) prevention bundle results in decreased MRSA surgical site infections
The American Journal of Surgery, 11/03/2009

Awad SS et al. – The data demonstrate that successful implementation of the MRSA bundle significantly decreases MRSA transmission between patients, the overall number of nosocomial MRSA infections, and MRSA SSIs [more...]

Twenty-five year epidemiology of invasive methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered at a burn center
Burns, 11/16/2009

Murray CK et al. – A transition was found in hospital–associated MRSA isolates over the 25 years, but no introduction of community–associated MRSA isolates into this burn unit. Continued active ... control strategies are recommended to prevent the spread of community–acquired MRSA to this burn unit. [more...]

Bench-to-bedside review: Understanding the impact of resistance and virulence factors on MRSA infections in the ICU
Critical Care, 10/27/2009

Skrupky LP et al. – Staphyloccocus aureus and MRSA can no longer be considered as solely a nosocomial pathogen. When initiating empiric antibiotics, it is of vital importance ... adverse outcomes. Although vancomycin has long been considered a first–line therapy for serious MRSA infections, multiple concerns with this agent have opened the door for existing and investigational agents demonstrating efficacy in this role. [more...]

Enhanced surveillance of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia in children in the UK and Ireland
BMJ - Archives of Diseases in Childhood, 10/29/2009

Johnson AP et al. – MRSA bacteraemia in children was relatively uncommon and was predominantly seen in very young children, often those receiving neonatal or paediatric ... epidemic strains of MRSA associated with nosocomial infection. [more...]

Staphylococcus aureus Endophthalmitis: Antibiotic Susceptibilities, Methicillin Resistance, and Clinical Outcomes
American Journal of Ophthalmology, 11/19/2009

Major JC et al. – Although all MSSA and MRSA isolates were sensitive to vancomycin, fewer than half of MRSA isolates were sensitive to the fourth–generation fluoroquinolones. Visual acuity outcomes between MRSA and MSSA eyes were not significantly different. [more...]

Clinical Importance of Purulence in Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections
Journal of the American Board of Family Medicine, 11/09/2009

Crawford SE et al. – A purulent MRSA SSTI strongly predicted the presence of a clindamycin–susceptible MRSA isolate. Presence of the pvl genes was almost universal among MRSA isolates causing purulent SSTIs; this was less common in nonpurulent SSTIs and [more...]

Aerosolized vancomycin for the treatment of MRSA after lung transplantation
Respirology, 11/10/2009

Hayes D et al. – Lung transplantation is the only life–prolonging therapy available for cystic fibrosis (CF) patients with end–stage lung disease. The presence of pathogens in the airways of CF patients ... MRSA) having a growing impact. Aerosolized vancomycin has been used successfully in the treatment of MRSA in the CF population but its use after lung transplantation has not been previously reported. The authors report the case of a lung transplant recipient who was successfully treated for MRSA [more...]

SpectraTM MRSA, A New Chromogenic Agar Medium to Screen for Methicillin-Resistant Staphylococcus aureus
Journal of Clinical Microbiology, 11/13/2009

Peterson JF et al. – The authors found that SpectraTM MRSA was able to rapidly identify and differentiate methicillin–resistant S. aureus from methicillin–susceptible S. aureus ... colonies, thus eliminating the need for biochemical analysis and antimicrobial susceptibility testing. Extending the incubation beyond 24 h did not significantly improve the recovery of MRSA and resulted in decreased specificity. [more...]

Should Vascular Surgery Patients Be Screened Preoperatively for Methicillin-Resistant Staphylococcus aureus
Infection Control and Hospital Epidemiology, 10/27/2009

Lee BY et al. – Testing and decolonizing patients for MRSA before vascular surgery may be a cost–effective strategy over a wide range of MRSA prevalence and decolonization success rates. [more...]

Empirical Antimicrobial Therapy for Bloodstream Infection Due to Methicillin-Resistant Staphylococcus aureus: No Better than a Coin Toss
Infection Control and Hospital Epidemiology, 10/14/2009

Only half of patients with MRSA BSI received appropriate empirical therapy. Factors associated with receiving appropriate empirical antibiotics included the presence of a central venous catheter at admission and a history of joint arthroplasty. Surprisingly, prior MRSA infection was not predictive [more...]