Top hepatitis c Articles in Infectious Disease

Acute hepatitis C and HIV coinfection
The Lancet Infectious Diseases, 11/19/2009

Dionne–Odom J et al. – The authors present a case of a man infected with HIV with sexually acquired acute hepatitis C and discuss the immunology, natural history, and epidemiology of acute hepatitis C and coinfection with HIV. Several recent ... documented acute hepatitis C among men who have sex with men who engage in high risk sexual practices and often have concomitant genital ulcer disease. [more...]

De novo hepatocellular carcinoma in a liver graft with sustained hepatitis C virus clearance after living donor liver transplantation
Liver Transplantation, 10/30/2009

Taketomi A et al. – This is the first report of de novo HCC in a liver graft with sustained hepatitis C virus clearance after LT for advanced HCCs and hepatitis C cirrhosis. [more...]

FOXP3 Expression in Hepatitis C Virus-Specific CD4+ T Cells During Acute Hepatitis C
Gastroenterology, 10/06/2009

Heeg MJH et al. – Although short–lived increases in HCV–specific FOXP3+CD4+ T cells occur during the course of acute hepatitis C, the authors could not demonstrate an association of HCV&ndash ... cells and persistent viremia. [more...]

Treatment modalities for hypersplenism in liver transplant recipients with recurrent hepatitis C
World Journal of Gastroenterology, 10/30/2009

Sibulesky L et al. – Hepatitis C is the most common indication for orthotopic liver transplantation in the United States. Unfortunately, hepatitis C recurs universally in the transplanted liver and is the major cause ... therapy of interferon and ribavirin has been shown to be the most effective therapy for recurrent hepatitis C. [more...]

Fibrosis progression in chronic hepatitis C: Morphometric image analysis in the HALT-C trial
Hepatology, 10/14/2009

Goodman ZD et al. – Morphometry demonstrated complex, nonlinear changes in fibrosis over time in this heterogeneous cohort of patients with interferon–refractory chronic hepatitis C. [more...]

The HLA-ER/HLA-ER Genotype Affects the Natural Course of Hepatitis C Virus (HCV) Infection and Is Associated with HLA-E–Restricted Recognition of an HCV-Derived Peptide by Interferon[gamma]–Secreting Human CD8+ T Cells
The Journal of Infectious Diseases, 10/14/2009

Schulte D et al. – The authors showed chronic hepatitis C to be associated with increased expression ... peptide hepatitis C virus (HCV) core amino acids 35–44 as a ligand for HLA-E that stabilizes HLA-E expression, favoring inhibition of natural killer cell cytotoxicity. The data indicate an important immunomodulating function of HLA-E in hepatitis C. [more...]

APRI as a predictor of early viral response in chronic hepatitis C patients
World Journal of Gastroenterology, 10/26/2009

Mata–Marin JA et al. – APRI was not a predictor of EVR in chronic hepatitis C; Genotype 1 was the only predictive factor associated with the absence of EVR in patients. [more...]

Factors influencing long-term changes in mental health after interferon-alpha treatment of chronic hepatitis C
Alimentary Pharmacology and Therapeutics, 10/23/2009

Schaefer M et al. – Pre–existing psychiatric risk factors increase the chance for a long–term improvement and reduce the risk for a long–term worsening of mental health after antiviral treatment of chronic hepatitis C with IFN–alpha ... other psychiatry,hepatitis,hepatology,basic science/genetics [more...]

Public health impact of antiviral therapy for hepatitis C in the United States
Hepatology, 10/14/2009

Volk ML et al. – Efforts to improve rates of diagnosis and treatment will be required if the future public health burden of hepatitis C is to be ameliorated. [more...]

Steatosis and hepatic expression of genes regulating lipid metabolism in Japanese patients infected with hepatitis C virus
Journal of Gastroenterology, 10/02/2009

Yasui K et al. – The findings indicate that impaired degradation of lipid may contribute to the development of hepatitis C virus–related steatosis. [more...]