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Bevacizumab in the treatment of breast cancer
Cancer Treatment Reviews, 11/25/09
Koutras AK et al. – Current evidence indicates that angiogenesis plays an important role in the pathogenesis of several malignancies, including breast cancer. Bevacizumab is a monoclonal antibody that targets the vascular endothelial growth factor (VEGF).
Results- Clinical data have demonstrated that addition of bevacizumab to first-line chemotherapy improves PFS of patients with advanced breast cancer
- Update on clinical studies evaluating role of bevacizumab in combination with chemotherapy, as well as other agents, both in advanced and early disease presented
Today in Breast...keeping you current
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Concurrent or sequential adjuvant letrozole and radiotherapy after conservative surgery for early-stage breast cancer (CO-HO-RT): A phase II randomised trial
The Lancet Oncology - Online First, 02/09/10
Comparison of patient-reported breast, arm, and shoulder symptoms and body image after radiotherapy for early breast cancer: 5-year follow-up in the randomised Standardisation of Breast Radiotherapy (START) trials
The Lancet Oncology - Online First, 02/09/10
Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
BMC Cancer, 02/09/10
Today in Pharmacology/Therapy...keeping you current
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Concurrent or sequential adjuvant letrozole and radiotherapy after conservative surgery for early-stage breast cancer (CO-HO-RT): A phase II randomised trial
The Lancet Oncology - Online First, 02/09/10
Plasma and cerebrospinal fluid pharmacokinetics of topotecan in a phase I trial of topotecan, tamoxifen, and carboplatin, in the treatment of recurrent or refractory brain or spinal cord tumors
Cancer Chemotherapy and Pharmacology, 02/09/10
A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer
Cancer Chemotherapy and Pharmacology, 02/09/10
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