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Association of rare MSH6 variants with familial breast cancer
Breast Cancer Research and Treatment, 11/25/09
Wasielewski M et al. – These data suggest that rare MSH6 variants may predispose to familial breast cancer. However, none of the rare MSH6 variants are obviously pathogenic, suggesting that a more subtle disease mechanism may operate in breast carcinogenesis.
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Today in Basic Science/Genetics...keeping you current
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Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
BMC Cancer, 02/09/10
TWIST1 hypermethylation is observed frequently in colorectal tumors and its overexpression is associated with unfavorable outcomes in patients with colorectal cancer
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Cancer Chemotherapy and Pharmacology, 02/09/10
Today in Breast...keeping you current
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Concurrent or sequential adjuvant letrozole and radiotherapy after conservative surgery for early-stage breast cancer (CO-HO-RT): A phase II randomised trial
The Lancet Oncology - Online First, 02/09/10
Comparison of patient-reported breast, arm, and shoulder symptoms and body image after radiotherapy for early breast cancer: 5-year follow-up in the randomised Standardisation of Breast Radiotherapy (START) trials
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Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
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Today in Carcinogenesis...keeping you current
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Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric cancer
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The clusterin paradigm in prostate and breast carcinogenesis
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