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Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia
Blood, 11/25/09
Kanduri M et al. – The data for the first time reveal differences in global methylation profiles between prognostic subsets of CLL, which may unfold epigenetic silencing mechanisms involved in CLL pathogenesis.
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Today in Basic Science/Genetics...keeping you current
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Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
BMC Cancer, 02/09/10
TWIST1 hypermethylation is observed frequently in colorectal tumors and its overexpression is associated with unfavorable outcomes in patients with colorectal cancer
Genes, Chromosomes and Cancer, 02/09/10
Plasma and cerebrospinal fluid pharmacokinetics of topotecan in a phase I trial of topotecan, tamoxifen, and carboplatin, in the treatment of recurrent or refractory brain or spinal cord tumors
Cancer Chemotherapy and Pharmacology, 02/09/10
Today in Leukemia/Lymphoma...keeping you current
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Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 study
American Journal of Hematology, 02/09/10
Role of denileukin diftitox in the treatment of persistent or recurrent cutaneous T-cell lymphoma
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Abnormal fatty acid distribution of the serum phospholipids of patients with non-Hodgkin lymphoma
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