Oncology

Your Article Summary

See Latest Articles

Treatment of squamous cell carcinoma of the uterine cervix with radiation therapy alone: long-term survival, late complications, and incidence of second cancers
British Journal of Cancer, 09/26/07

Ota, T., et al. - In a study to determine the survival rate, incidence of late complications, and incidence of second cancers when radiation therapy alone is used for carcinoma of the uterine cervix, it was found that this method of radiation therapy alone for locally advanced carcinoma of the uterine cervix is effective, with low incidences of late complications and second cancers

• 1495 patients with squamous cell carcinoma of the uterine cervix (stages I-IV) were treated with radiation therapy alone
• Radiation therapy consisted of a combination of high-dose-rate intracavitary brachytherapy and external beam radiotherapy

• Cumulative 5-year survival rates for stages Ib, II, and III/IVa carcinoma were 93.5, 77.0, and 60.3%, respectively
• 10-year survival rates were 90.9, 74.5, and 56.1%, respectively
• Local control rates for stages Ib, II, and III/IVa carcinoma were 92.0, 79.4 and 64.2%, respectively
• 5.5% of patients suffered grade III/IV or V (fatal) complications
• A second cancer developed in 0.87% of patients
• Second cancers were observed most frequently in the rectum (5 cases), colon (3 cases), and uterine body (2 cases)

Today in Gynecologic Oncology...keeping you current

Receive free subspecialty "5-minute updates" via email

Dose-dense paclitaxel once a week in combination with carboplatin every 3 weeks for advanced ovarian cancer: A phase 3, open-label, randomised controlled trial
The Lancet, 11/23/09

Elevated expression of p53 gain-of-function mutation R175H in endometrial cancer cells can increase the invasive phenotypes by activation of the EGFR/PI3K/AKT pathway
Molecular Cancer, 11/20/09

Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors
Journal of Cancer Research & Clinical Oncology, 11/20/09

 See all of Gynecologic Oncology