Management of hematological malignancies during pregnancy
American Journal of Hematology, 10/27/2009
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Rizack T et al. – The purpose of this review is to evaluate the limited existing data and make useful suggestions in the management of acute and chronic leukemias, Hodgkin and non–Hodgkin lymphomas, plasma cell myeloma, and ... hematological malignancies, such as myelodysplastic syndromes and hairy cell leukemia, during pregnancy.
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Risk factors for acute respiratory distress syndrome during neutropenia recovery in patients with hematologic malignancies
Critical Care, 11/06/2009
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Rhee CK et al. – Neutropenia recovery may be associated with deterioration in oxygenation and exacerbation of pre–existing pulmonary disease. However, risk factors ... hematologic malignancies have not been studied. Patients with hematologic malignancies complicated by pneumonia during neutropenia are at increased risk for ARDS during neutropenia recovery.
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Targeting the Warburg effect in hematological malignancies: from PET to therapy
Current Opinion in Oncology, 10/14/2009
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Shanmugam M et al. – Targeting the glycolytic pathway for the treatment of hematological malignancies has sufficient rationale given the utility of 18fluoro–deoxyglucose positron emission tomography in
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Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia
European Journal of Haematology, 11/04/2009
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Karimi M et al. – Combination of hydroxyurea with l–carnitine or magnesium could be more effective in improving hematologic parameters and cardiac status in
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Tumor lysis and acute renal failure in Burkitt's lymphoma: A review on pathophysiology and management
Indian Journal of Nephrology, 10/16/2009
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in patients with Burkitt's lymphoma, the commonest hematological malignancy in the pediatric age group in sub–Saharan Africa, and evaluates the possible management options. Tumor lysis can also develop in association with other hematologic malignancies, both spontaneously and following
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Diagnostic Efficacy and Safety of Computed Tomography-Guided Transthoracic Needle Biopsy in Patients with Hematologic Malignancies
Academic Radiology, 10/21/2009
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Kallenberg MH et al. – TTNB is a safe diagnostic procedure in patients with hematologic malignancies and has the potential of making specific diagnoses with minimal morbidity.
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Management of Hepatitis B Virus Reactivation in Patients with Hematological Malignancies Treated with Chemotherapy
Infection, 11/19/2009
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Francisci D et al. – Essential to the management of patients with hematological malignancies undergoing chemotherapy are surveillance and prophylaxis of HBV infection together
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Influence of Lymphocyte Recovery on Outcome of Haploidentical Transplantation for Hematologic Malignancies
Medicine, 11/20/2009
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Chang YJ et al. – The results suggest that the recovery of ALC–30 might have an influence on transplant outcomes following unmanipulated HLA–mismatched/haploidentical transplantation.
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A Phase 1 Dose Escalation Study of the Safety and Pharmacokinetics of the Novel Proteasome Inhibitor Carfilzomib (PR-171) in Patients with Hematologic Malignancies
Clinical Cancer Research, 11/16/2009
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O'Connor OA et al. – This is the first clinical use of carfilzomib that shows tolerability and clinical activity in multiple hematologic malignancies using consecutive–day dosing
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Epigenetic Inactivation of the Circadian Clock Gene BMAL1 in Hematologic Malignancies
Cancer Research, 11/03/2009
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Taniguchi H et al. – The DNA hypermethylation–associated loss of BMAL1 also prevents the recruitment of its natural partner, the CLOCK protein, to their common targets, further enhancing the perturbed ... that BMAL1 epigenetic inactivation contributes to the development of hematologic malignancies by disrupting the cellular circadian clock.
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