Top hcc Articles in Oncology

Genomic aberrations in hepatocellular carcinoma related to osteopontin expression detected by array-CGH
Journal of Cancer Research & Clinical Oncology, 10/23/2009

There is a significant intratumor genomic heterogeneity between the OPN–positive and negative HCC cells, and OPN–positive HCC cells play a more important role in the development of HCC malignancy than their OPN–negative counterparts. [more...]

Prognostic factors and recurrence of hepatitis B-related hepatocellular carcinoma after argon-helium cryoablation: a prospective study
Clinical and Experimental Metastasis, 10/02/2009

The expression of VEGF in HCC tissues and HBV BCP mutations were found to be independent prognostic factors for recurrence–free survival. Strong expression of VEGF in HCC tissues and HBV BCP mutations are important risk predictors for recurrence or metastasis of HCC smaller than 5 cm in [more...]

Recurrence of hepatocellular carcinoma and hepatitis B reinfection in hepatitis B surface antigen-positive patients after liver transplantation
Liver Transplantation, 11/03/2009

al. – Pre–OLT HCC and HCC recurrence after transplantation were associated with HBV reinfection and with decreased patient survival. Hepatitis B immunoglobulin and antiviral therapy was only partially effective in preventing HBV reinfection in patients with HCC recurrence [more...]

Multidetector-row computed tomography (MDCT) for the diagnosis of hepatocellular carcinoma in cirrhotic candidates for liver transplantation: prevalence of radiological vascular patterns and histological correlation with liver explants
European Radiology, 10/06/2009

by MDCT can be confidently considered to be HCC. Hyper–L larger than 10 mm and Hypo–L of 20 mm or larger are at high risk of HCC. However, even using MDCT and the newest imaging protocols, imaging underestimated the diagnosis of small HCC. [more...]

Role of Hepatitis B Virus Infection in the Prognosis After Hepatectomy for Hepatocellular Carcinoma in Patients With Cirrhosis
Archives of Surgery, 10/20/2009

for lower RFS after hepatectomy for a single nodule of HCC of 5 cm or smaller in patients with cirrhosis, providing a further basis for adjuvant antiviral treatment. Patients who are seropositive for HBV with poorly differentiated HCC should also be considered to be at a high risk of recurrence and [more...]

Predictors and prognostic significance of operative complications in patients with hepatocellular carcinoma who underwent hepatic resection
European Journal of Surgical Oncology, 10/21/2009

of complications after hepatic resection for HCC. Long–term survival is poorer in patients with postoperative complications. Decreasing operative blood loss may result in fewer postoperative complications and better long–term survival of HCC patients. [more...]

Decreased expression of Neurensin-2 correlates with poor prognosis in hepatocellular carcinoma
World Journal of Gastroenterology, 10/20/2009

Ma HQ et al. – The authors study indicated that NRSN2 could be a tumor suppressor gene for HCC and a candidate biomarker for long–term survival in HCC. [more...]

Pre-S2 deletions of hepatitis B virus and hepatocellular carcinoma in children
Pediatric Research, 10/09/2009

does not need to take decades to occur; its presence in nearly half of children with HCC, in contrast to its absence in children with chronic HBV infection, suggests a link between pre–S2 deletion and HCC development in children. [more...]

Liver transplantation versus liver resection for the treatment of hepatocellular carcinoma
Journal of Surgical Oncology, 10/05/2009

Lee KK et al. – LT should be considered as the primary treatment in patients with HCC within the Milan criteria. LR is recommended for patients with HCC beyond the Milan criteria. The LT group showed a significantly lower recurrence rate than the LR group. However [more...]

Predicting recurrence after liver transplantation in patients with hepatocellular carcinoma exceeding the up-to-seven criteria
Liver Transplantation, 10/02/2009

D'Amico F et al. – HCC patients within the pathologic Up–to–7 criteria were associated with a low risk of recurrence after LT. Beyond these criteria, however, a significant proportion of patients with a good HCC biological profile had an acceptable risk of [more...]