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Cobble M et al. – Carotid intima–media thickness (CIMT), as measured by B–mode ultrasound, is a surrogate marker for atherosclerosis and can be used to detect an accelerated disease process and subclinical disease. Advantages of CIMT are that it is noninvasive, relatively inexpensive, and can be repeatedly performed with no adverse effects on the patient. Carotid intima–media thickness is associated with CVD and is an independent predictor of stroke and myocardial infarction. Therefore, CIMT is valuable for clarifying CVD risk, particularly for patients with intermediate risk by conventional risk assessment. Screening for subclinical disease even in low–risk patients may have benefit, especially for those with a family history of premature CVD or those with any of the National Cholesterol Education Program risk factors.


Exclusive Author Commentary
Michael Cobble, 01/09/10

Happy New Year 2010. Nice summary for a test which is easy to apply in clinical practice and helps with patient risk identification and management. If one should see atheroma or intimal disease it allows the clinician to target risk factors and lipids more progressively to stabilize atherosclrosis. Feel free to email with questions, we have been using this test for years to complement practice and patient care and will be happy to answer questions about it's utility. Enjoy. Mike Cobble, M.D.

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