Cardiology Medical News about Aged Cardiomyopathy, Hypertrophic

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Hypertrophic cardiomyopathy in the elderly
Geriatrics and Gerontology International, 11/17/09

Kubo T et al. – Cardiac hypertrophy that becomes clinically apparent late in life can be a genetic disorder, and mutations in the cardiac myosin–binding protein C gene are the most common cause of late–onset or elderly hypertrophic cardiomyopathy (HCM). In the morphological features, sarcomere gene defects seem to have a predilection for a crescent–shaped left ventricular cavity with reversed septal curvature even in elderly patients, although an ovoid left ventricular shape was frequently seen in elderly patients in previous clinical studies on morphological characteristics of HCM. In middle–aged or elderly patients with HCM, heart failure and embolic events, which were strongly associated with atrial fibrillation, were very important. It is important to manage HCM patients from the standpoint of longitudinal evolution in order to prevent those clinical complications.

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