Prevention of atherosclerosis with low-density lipoprotein cholesterol lowering—lipoprotein changes and interactions: the SANDS study
Journal of Clinical Lipidology, 10/14/2009
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Howard WJ et al. – In diabetic adults with no previous cardiovascular events, treatment to current targets for lipids and systolic blood pressure reduces atherosclerosis ... targets are met, atherosclerosis regresses. The aggressive targets for LDL–C and non–HDL–C appeared to be the main determinants of CIMT regression and were more predictive of this outcome than changes in LDL–P or apoB.
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Periodontal treatment influences risk markers for atherosclerosis in patients with severe periodontitis
Atherosclerosis, 10/09/2009
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Buhlin K et al. – This study indicates that standard treatment for periodontal disease induces systemic changes in several biochemical markers that reflect the risk for atherosclerosis.
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Liver X Receptors as potential therapeutic targets in atherosclerosis
Clinical and Investigative Medicine, 10/06/2009
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Zhu Y et al. – LXR –selective agonists and LXR modulators, which act as agonists in macrophages and induce cholesterol efflux while as antagonists of lipogenesis in the liver, are two critical and attractive approaches to treat atherosclerosis and ... diseases.
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Effects of High-Dose Modified-Release Nicotinic Acid on Atherosclerosis and Vascular Function: A Randomized, Placebo-Controlled, Magnetic Resonance Imaging Study
JACC - Journal of the American College of Cardiology, 10/29/2009
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Lee JMS et al. – In statin–treated patients with low HDL–C, high–dose modified–release NA, compared with placebo, significantly reduces carotid atherosclerosis ... within 12 months.
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Blood Glutathione and Subclinical Atherosclerosis in African Men: The SABPA Study
American Journal of Hypertension, 10/28/2009
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Schutte R et al. – In hypertensive African men, CIMT is negatively associated with GSH, suggesting a possible contributory role of attenuated GSH levels in the development of subclinical atherosclerosis.
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Effects of Bariatric Surgery on Inflammatory, Functional and Structural Markers of Coronary Atherosclerosis
The American Journal of Cardiology, 10/21/2009
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Habib P et al. – GBS results in significant improvements in inflammatory, structural, and functional markers of coronary atherosclerosis.
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18F-4V for PET–CT Imaging of VCAM-1 Expression in Atherosclerosis
JACC - Journal of the American College of Cardiology: Cardiovascular Imaging, 10/19/2009
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Nahrendorf M et al. – 18F–4V allows noninvasive PET–CT imaging of VCAM–1 in inflammatory atherosclerosis, has the dynamic range to quantify treatment effects, and correlates with inflammatory gene expression.
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High-Density Lipoprotein–Based Contrast Agents for Multimodal Imaging of Atherosclerosis
Arteriosclerosis, Thrombosis, and Vascular Biology, 10/16/2009
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Skajaa T et al. – By rerouting of HDL away from plaque macrophages, imaging of biological processes in diseases besides atherosclerosis may also be achieved.
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Visfatin (Nampt) and Ghrelin as Novel Markers of Carotid Atherosclerosis in Patients with Type 2 Diabetes
Experimental and Clinical Endocrinology & Diabetes, 10/21/2009
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Kadoglou NPE et al. – High nampt and low ghrelin serum levels are significantly associated with advanced carotid atherosclerosis in patients with T2DM. Moreover these adipocytokines are ... role as novel atherosclerotic biomarkers and providing another important link between adiposity and atherosclerosis.
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Arterial Atherosclerosis in Patients With Chronic Kidney Disease and Its Relationship With Serum and Tissue
Iranian Journal of Kidney Diseases, 10/13/2009
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Noshad H et al. – Tissue endothelin–1 concentration is more important than serum endothelin–1 or lipids levels in prediction of atherosclerosis. Thus, blockade of tissue ... ndash;1 receptors with its antagonists may prevent atherosclerosis progression.
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