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KRAS Mutational Status as a Predictor of Epidermal Growth Factor Receptor Inhibitor Efficacy in Colorectal Cancer
American Journal of Therapeutics, 11/25/09
Baynes RD et al. – There has been growing interest in the development of KRAS mutational status as a biomarker for predicting patient response to EGFR–targeted therapy. Screening colorectal tumors for the absence of KRAS mutations may help identify patients most likely to benefit from anti–EGFR therapies.
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