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Cho SH et al. - In a trial to evaluate the efficacy and safety of concurrent chemoradiotherapy with S-1 and cisplatin in advanced esophageal cancer, it was shown that the main hematological toxicity was neutropenia, but no neutropenic fever was observed. The major non-hematological toxicities were asthenia and vomiting, mostly of grades 1 and 2. Concurrent chemoradiotherapy with S-1 and cisplatin may be a promising nonsurgical treatment in advanced esophageal cancer

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