Gastro Medical News about Lactobacillus acidophilus

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Antigen-presenting cells exposed to Lactobacillus acidophilus NCFM, Bifidobacterium bifidum BI-98, and BI-504 reduce regulatory T cell activity
Inflammatory Bowel Disease, 09/03/09

Kristensen NN et al. – The authors conclude that certain probiotic strains can modify APCs to cause reduced Treg activity. This effect apparently depends on a direct APC–to–Treg cell contact. The APC–mediated suppressive effect on Treg function of certain probiotic strains may constrain the anti–inflammatory activity, which is often desired from probiotic therapy. This unexpected function of certain probiotic strains should be taken into consideration when designing adjuvant therapies with these bacteria, or when probiotic strains are selected for improvement of gut–associated inflammation like IBD.

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Lactobacillus GG Improves Recovery in Infants with Blood in the Stools and Presumptive Allergic Colitis Compared with Extensively Hydrolyzed Formula Alone
The Journal of Pediatrics, 11/03/09 Relevance Score: 40%

CD4+ T Cells and Lactobacillus casei Control Relapsing Colitis Mediated by CD8+ T Cells
Journal of Immunology, 10/22/09 Relevance Score: 40%

Gut commensal Lactobacillus reuteri 100-23 stimulates an immunoregulatory response
Immunology & Cell Biology, 10/05/09 Relevance Score: 40%

Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome
Neurogastroenterology and Motility, 11/11/09 Relevance Score: 39%