Gastro Medical News about iron overload diseases

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A novel missense mutation in SLC40A1 results in resistance to hepcidin and confirms the existence of two ferroportin-associated iron overload diseases
British Journal of Haematology, 08/27/09

Letocart E et al. – By contrast, it was resistant to inhibition by hepcidin. These findings confirm that certain ferroportin mutations compromise the activity of hepcidin in iron homeostasis, mimicking hepcidin deficiency as described in all types of hemochromatosis.

Hepatic Iron Deposition in Patients With Liver Disease: Preliminary Experience With Breath-Hold Multiecho T2-Weighted Sequence
American Journal of Roentgenology, 11/04/09 Relevance Score: 80%

Hepatitis C comorbidities affecting the course and response to therapy
World Journal of Gastroenterology, 10/30/09 Relevance Score: 78%

Advances in the Prevention and Treatment are Changing Thalassemia from a Fatal to a Chronic Disease. Experience from a Cyprus Model and its Use as a Paradigm for Future Applications
Hemoglobin, 10/23/09 Relevance Score: 78%

Fanconi Syndrome and CKD in a Patient With Paroxysmal Nocturnal Hemoglobinuria and Hemosiderosis
American Journal of Kidney Diseases, 10/16/09 Relevance Score: 78%

Ulcerative leg nodules in a transplant recipient
Cleveland Clinic Journal of Medicine, 10/16/09 Relevance Score: 77%