Gastro Medical News about Kaposi’s sarcoma

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Safety and efficacy of pegylated liposomal doxorubicin in HIV-associated Kaposi's sarcoma
Biologics: targets & therapy, 08/17/09

Cainelli F et al. – The drug in this formulation localizes better to the tumor and has higher efficacy. Skin toxicity, mucositis, and leukopenia/neutropenia are the main side effects. Hepatotoxicity and mild cardiotoxicity are observed less frequently. Pegylated liposomal doxorubicin impacts favorably on quality of life. Although cost effective in Western countries, the drug is less so in developing countries.