Antigen-presenting cells exposed to Lactobacillus acidophilus NCFM, Bifidobacterium bifidum BI-98, and BI-504 reduce regulatory T cell activity
Inflammatory Bowel Disease, 09/03/2009
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The authors conclude that certain probiotic strains can modify APCs to cause reduced Treg activity. This effect apparently depends on a direct APC–to–Treg cell contact. The APC–mediated suppressive effect on Treg function of certain probiotic strains may constrain the anti&ndash ... often desired from probiotic therapy. This unexpected function of certain probiotic strains should be taken into consideration when designing adjuvant therapies with these bacteria, or when probiotic strains are selected for improvement of gut–associated inflammation like IBD
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Targeting the vaginal microbiota with probiotics as a means to counteract infections
Current Opinion in Clinical Nutrition & Metabolic Care, 10/27/2009
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Reid G et al. – The mechanisms whereby certain probiotic lactobacilli improve urogenital health include immune modulation, pathogen displacement and creation of a niche less conducive to proliferation of ... Probiotics offer a potential new means to prevent urogenital infections and help maintain a healthy vaginal ecosystem.
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Use of Probiotics in the Management of Chemotherapy-Induced Diarrhea: A Case Study
Journal of Parenteral and Enteral Nutrition, 09/02/2009
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Hegazi R et al. – The case study demonstrates that the probiotics can also be used to treat severe cases of chemotherapy–induced diarrhea in breast cancer patients. The use of different probiotics in ... gastrointestinal diseases is an increasingly important area of study, and more research into this area is needed. This study demonstrates that probiotics should be considered for advanced breast cancer patients with chemotherapy–induced diarrhea.
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Effect of probiotic supplementation on immunoglobulins, isoagglutinins and antibody response in children of low socio-economic status
European Journal of Nutrition, 10/21/2009
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Pérez N et al. – Supplementation of standard fermented milk with additional probiotics was not of benefit. The high natural rate of early microbial exposure ... and children from a population of low socio–economic status living in a “less hygienic environment” may account for the absence of an additional immune–stimulating effect by supplementary probiotics.
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Probiotics Reduce the Risk of Necrotizing Enterocolitis in Preterm Infants
Neonatology, 08/25/2009
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AlFaleh K et al. – Enteral supplementation of probiotics reduces the risk of severe NEC and mortality in preterm infants. A large randomized controlled trial is required to investigate the benefit and safety profile ... of probiotics supplementation in ELBW infants.
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A probiotic dairy product containing L. gasseri CECT5714 and L. coryniformis CECT5711 induces immunological changes in children suffering from allergy
Pediatric Allergy and Immunology, 08/28/2009
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Martinez–Canavate A et al. – The daily consumption of a probiotic product containing L. gasseri CECT5714 and L. coryniformis CECT5711 ... effects on immune parameters involved in the allergic response such as a reduction of IgE in plasma and an increase in regulatory T cells. The probiotic product also enhanced innate and specific immune parameters that may improve the general health status of children.
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Coaggregation between probiotic bacteria and caries-associated strains: An in vitro study
Acta Odontologica Scandinavica, 08/17/2009
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Twetman L et al. – The results demonstrated different abilities of lactobacilli–derived probiotic bacteria to coaggregate with selected oral streptococci. Aggregation assays may be a useful ... probiotic candidates with possible anti–caries properties.
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Blueberry husks, rye bran and multi-strain probiotics affect the severity of colitis induced by dextran sulphate sodium
Scandinavian Journal of Gastroenterology, 09/24/2009
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Hakansson A et al. – A combination of probiotics and blueberry husks or rye bran enhanced the anti–inflammatory effects compared with probiotics or dietary fibres alone. These
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Effects of the enteral administration of Bifidobacterium breve on patients undergoing chemotherapy for pediatric malignancies
Supportive Care in Cancer, 08/21/2009
probiotic or placebo.The effects on infectious complications, natural killer cells, fecal micro flora, fecal organic acid concentrations, and fecal pH were studied.Results- Frequency of fever and use of intravenous antibiotics were lower in the probiotic group ... li>
- Probiotic administration enhanced the habitation of anaerobes.
- Disruption of the intestinal microbiota after chemotherapy such as increase in population levels of Enterobacteriaceae was observed at more pronounced manner in the placebo group in comparison with the probiotic group.
probiotic group.
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The effects of selected probiotic strains on the development of eczema (the PandA study)
Allergy, 08/25/2009
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Niers L et al. – The particular combination of probiotic bacteria shows a preventive effect on the incidence of eczema in high–risk children, which seems to be sustained during the first 2 years of
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