Increased frequency of gastrointestinal symptoms in patients with fibromyalgia and associated factors: A comparative study
Journal of Rheumatology, 08/14/2009
Pamuk ON et al. – Study reports that in patients with fibromyalgia (FM), the severity scores of dyspepsia symptoms, constipation, and dyspepsia-related quality of life (QOL) disturbance were higher than in patients with rheumaotid arthritis (RA) and controls. The higher ... Symptoms of FM Symptoms of dyspepsia, using a VAS and anxiety-depression scale Pts were asked self-reported: - Symptom-based constipation and severity of constipation questions, and
- About the severity of QOL disturbance secondary to dyspepsia and constipation
Pts with FM had more dyspepsia-related QOL disturbances vs other 2 groups FM and RA pts had more frequent self-reported constipation than controls Frequency of symptom
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Correlations Among Electrogastrogram, Gastric Dysmotility, and Duodenal Dysmotility in Patients With Functional Dyspepsia
Journal of Clinical Gastroenterology, 08/21/2009
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Sha W et al. – More than two–thirds of patients with functional dyspepsia have abnormalities in the EGG and antral/duodenal motility. The sensitivity of these 2 different ... demonstrating gastric motor dysfunction in patients with functional dyspepsia.
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A possible association between maternal dyspepsia and congenital rectal/anal atresia/stenosis in their children: a population-based case-control study
Acta Obstetricia et Gynecologica Scandinavica, 08/19/2009
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Acs N et al. – Severe chronic dyspepsia in early pregnancy and drug treatment for this was not associated with a higher risk of CAs, except ... stenosis.
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Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic disease
Journal of Gastroenterology, 11/02/2009
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Sai JK et al. – Camostat mesilate may serve as a therapeutic agent for patients with dyspepsia associated with mild pancreatic disease, who do not habitually drink alcohol ... motility
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Novel associations with dyspepsia: a community-based study of familial aggregation, sleep dysfunction and somatization
Neurogastroenterology and Motility, 08/26/2009
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Talley NJ et al. – Diet, including total calories and total protein, carbohydrate and fat intake, was not significantly associated with dyspepsia. Familial aggregation ... genetic component, although environmental factors also need to be considered. Sleep dysfunction and somatization suggest a primary psychological component.
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Serum macrophage migration-inhibitory factor as a diagnostic and prognostic biomarker for gastric cancer
Cancer, 08/20/2009
cancer in pts presenting with dyspepsia and its prognostic value for gastric cancer, it was reported that serum MIF level, which correlates with gastric MIF expression, is a better molecular marker than CEA in diagnosing gastric cancer in pts presenting with dyspepsia. A combination of serum MIF and ... survival better than the individual test. Methods- 97 pts with histologically confirmed gastric adenocarcinoma and 222 pts with dyspepsia were recruited.
- Enzyme-linked immunosorbent assay was used to measure serum MIF and CEA.
Results
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Managing dyspepsia
Current Gastroenterology Reports, 08/10/2009
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Ford AC et al. – Recent evidence suggests that empirical acid suppression commencing with antacids is as effective as PPI. Screening and treatment of H. pylori in PPI users and the community may reduce the costs of managing dyspepsia.
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Stress profile, coping style, anxiety, depression, and gastric emptying as predictors of functional dyspepsia: A case-control study
Journal of Psychosomatic Research, 09/30/2009
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De la Roca–Chiapas JM et al. – The findings indicate that psychosocial stress, mood symptoms, and coping style are predictors of FD. The stress shows high ... etiopathogenesis of dyspepsia.
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Is there any association between disturbed gastrointestinal visceromotor and sensory function and impaired quality of life in functional dyspepsia
Neurogastroenterology and Motility, 10/12/2009
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Holtmann G et al. – In EPS and PDS, delayed gastric empting and altered sensory function are disease markers but not directly linked to the severity of HRQOL impairment or clinical presentation of FD.
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Functional Dyspepsia: Validation and Results of a Novel Survey Instrument to Evaluate Patient Knowledge and Perceptions
Journal of Clinical Gastroenterology, 10/21/2009
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Kennedy AT et al. – The novel questionnaire demonstrated good validity and reliability in FD patients, and identified significant misperceptions about the etiology ... treatment, and natural history of FD.
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