Medical Management of Ulcerative Colitis
Digestive Diseases, 11/09/2009
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Rogler G – Different therapy strategies are applied in ulcerative proctitis, left–sided colitis, pancolitis and fulminant colitis as well as in chronic active disease and maintenance of remission. This overview presents important concepts in the ... published guidelines.
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Oxidized Form Of A Common Vitamin May Bring Relief For Ulcerative Colitis
ScienceDaily, 10/02/2009
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A new research suggests that retinoic acid, the oxidized form of vitamin A, could be a beneficial treatment for people suffering from ulcerative colitis and other irritable bowel diseases. Specifically they found that ... which is a hallmark of active ulcerative colitis.
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Microscopic colitis: a review for the surgical endoscopist
Canadian Journal of Surgery, 10/16/2009
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Datta I et al. – Microscopic colitis (MC) is an inflammatory condition of the colon distinct from Crohn disease or ulcerative colitis that can cause chronic diarrhea as well as cramping and bloating. Treatment is initially supportive ... resistant cases. Since surgeons perform a large number of colonoscopies and sigmoidoscopies to assess diarrhea, it is important to be aware of this disease and to look for it with mucosal biopsy in appropriate patients.
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CD4+ T Cells and Lactobacillus casei Control Relapsing Colitis Mediated by CD8+ T Cells
Journal of Immunology, 10/22/2009
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Hacini–Rachinel F et al. – The data demonstrate that CD4+ regulatory T cells exert a protective effect on colitis by controlling colitogenic effector/memory CD8+ T cells during the effector (symptomatic) phase of acute and relapsing colitis ... respectively. Probiotics with natural adjuvant effects on mucosal regulatory T cells may represent a valuable approach to alleviate the colitogenic effect of Tc1–type CD8+ effectors.
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Ischemic Colitis After Endovascular Aortoiliac Aneurysm Repair
Archives of Surgery, 10/20/2009
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Miller A et al. – The incidence of ischemic colitis is decreased in patients undergoing EVAR vs open repair. The cause of the ischemia is multifactorial and seems to differ between patients in the early and late groups ... tends to produce severe ischemic colitis and is usually fatal. There should be a low threshold for performing endoscopy in any patient thought to have ischemic colitis after EVAR.
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Aldehyde Dehydrogenase–Expressing Colon Stem Cells Contribute to Tumorigenesis in the Transition from Colitis to Cancer
Cancer Research, 10/27/2009
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Carpentino JE et al. – Patients with chronic ulcerative colitis are at increased risk of developing colorectal cancer. Although current hypotheses suggest that sporadic ... not yet been validated in colitis–associated cancer. These data link colitis and cancer identifying potential tumor–initiating cells from colitic patients, suggesting that sphere and/or xenograft formation will be useful to survey colitic patients at risk of developing cancer.
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Mycophenolate Mofetil-induced Colitis in Children
Journal of Clinical Gastroenterology, 10/21/2009
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Phatak UP et al. – The cases underscore the importance of considering MMF–induced colitis in any patient who presents with diarrhea while on MMF therapy.
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Colectomy Rate Comparison After Treatment of Ulcerative Colitis With Placebo or Infliximab
Gastroenterology, 10/06/2009
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Sandborn WJ et al. – Patients with moderately to severely active ulcerative colitis treated with infliximab were less likely to undergo colectomy through 54 weeks than those receiving placebo ... pharmacology/kinetics,stomach/gi
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Ulcerative Colitis Treatment Reduces Need For Surgery By Almost Half, Study Suggests
ScienceDaily, 10/02/2009
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A new study has found that ulcerative colitis patients had a 41 percent reduction in colectomy after a year when treated with infliximab, according to a study.
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An Association Between Microscopic Colitis and Celiac Disease
Clinical Gastroenterology and Hepatology, 11/05/2009
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Green PHR et al. – Microscopic colitis is more common in patients with celiac disease than in the general population. Patients with celiac disease and microscopic colitis have more severe villous atrophy and frequently require
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