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Association between interleukin-1 beta polymorphism (+3953) and obesity
Molecular and Cellular Endocrinology, 11/25/09
Manica–Cattani MF et al. – The authors observed higher T allele (CT/TT) frequency in non–overweight than overweight and obese groups. The odds ratio showed 1.340 (95% CI: 1.119–1.605) times more chance of the obese group being CC carriers compared to non–overweight group independent of sex and age. This study corroborates the idea that the IL–1 system is linked to the development of obesity.
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