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Effects of Olanzapine and Haloperidol on the Metabolic Status of Healthy Men
Journal of Clinical Endocrinology and Metabolism, 11/25/09
Vidarsdottir S et al. – Short–term treatment with olanzapine reduces fasting plasma free fatty acid concentrations and hampers insulin action on glucose disposal in healthy men, whereas haloperidol has less clear effects. Moreover, olanzapine, but not haloperidol, blunts the insulin–induced decline of plasma free fatty acids and triglyceride concentrations. Notably, these effects come about without a measurable change of body fat mass.
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