Emergency Med

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Long-term immunosuppression in burned patients assessed by in vitro neutrophil oxidative burst (Phagoburst)
Burns, 09/13/07

Parment, K., et al. - Conclusions: This study provides evidence that immunosuppression in those injured by burns, as assessed by the in vitro oxidative burst of neutrophils, remains long after the event of the burn (up to 3.5 months after burn). Absence of correlations to TBSA%, FTB%, blood transfusion, opiates provided, and multiple organ failure score and laboratory infection variables together with the finding that decreased oxidative burst was uniform after the injury, suggesting that this immunosuppression is primarily due to the general metabolic response rather than recurring infections

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