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Expression of Fractalkine Receptor CX3CR1 on Cochlear Macrophages Influences Survival of Hair Cells Following Ototoxic Injury
Journal of the Association for Research in Otolaryngology, 11/25/09
Sato E et al. – The authors suggest that CX3CR1 plays a role in modulating the detrimental effects of cochlear macrophages after kanamycin ototoxicity. The data point to the possibility that CX3CR1–deficient cochlear macrophages exacerbate kanamycin ototoxicity while CX3CR1–expressing monocytes do not.
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