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Sabroe RA – Cholinergic urticaria is one of the more common physical urticarias. Although it is often fairly mild, severe treatment–resistant disease may occur, with significant associated disability. Omalizumab, a monoclonal IgG anti–IgE antibody licensed for use in severe asthma, has recently been used successfully in several types of urticaria, including in one case of cholinergic urticaria.


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