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Molecular pathogenesis of malignant melanoma: a different perspective from the studies of melanocytic nevus and acral melanoma
Pigment Cell & Melanoma Research, 10/19/09

Takata M et al. – Amplifications of the cyclin D1 gene are detected in normal–looking 'field melanocytes', which represent a latent progression phase of acral melanoma that precedes the stage of atypical melanocyte proliferation in the epidermis.

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