Dermatology Medical News about Purpura Purpura, Thrombocytopenic Purpura, Thrombotic Thrombocytopenic

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Deficiency of ADAMTS13 in thrombotic thrombocytopenic purpura
International Journal of Hematology, 10/12/09

Tsai H–M – Mutations of the gene are detected in patients with the congenital form of thrombotic thrombocytopenic purpura. In the circulation, proteolysis of von Willebrand factor is critical in regulating vWF–platelet interaction. These advances in knowledge provide the basis for a rational approach to improving the diagnosis and treatment of thrombotic thrombocytopenic purpura.

Priapism and Penile Gangrene Due to Thrombotic Thrombocytopenic Purpura
Urology, 11/09/09 Relevance Score: 96%

Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease domain reduces secretion and substrate turnover in a patient with congenital thrombotic thrombocytopenic purpura
Blood, 10/02/09 Relevance Score: 96%

Clinical-Pathological Features and Prognosis of Thrombotic Thrombocytopenic Purpura in Patients With Lupus Nephritis
The American Journal of the Medical Sciences, 11/13/09 Relevance Score: 95%

Lessons from acute pancreatitis-induced thrombotic thrombocytopenic purpura
European Journal of Internal Medicine, 11/11/09 Relevance Score: 95%

Rituximab was effective on refractory thrombotic thrombocytopenic purpura but induced a flare of hemophagocytic syndrome in a patient with systemic lupus erythematosus
Modern Rheumatology, 10/22/09 Relevance Score: 95%