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High dose dexamethasone regulates interleukin-18 and interleukin-18 binding protein in idiopathic thrombocytopenic purpura
Haematologica, 10/07/09
Shan N et al. – In vitro, DXM had a significant effect on secretion of IL–18BP while diminishing IL–18 release from cultures of PBMCs. These results suggest that downregulation of IL–18/IL–18BP might account for its clinical efficacy of HD–DXM in active ITP.
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Serum calcium levels are elevated among women with untreated postmenopausal breast cancer
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