Top rosacea Articles in Dermatology

Treatment Options for Acne Rosacea
American Family Physician, 08/31/2009

Goldgar C et al. – Rosacea is a common chronic, and sometimes progressive, dermatosis. It is characterized, alone or in combination, by central facial erythema, symmetric flushing, stinging sensation, inflammatory lesions (papules and pustules ... tissue hyperplasia and nodules). Rosacea can occur in adults of any ethnicity, and adversely affects patients' quality of life. The condition can be effectively controlled with therapy tailored to the specific subtype of rosacea that is affecting the patient. Topical metronidazole, sulfacetamide ... generally effective for patients with mild rosacea. For moderate papulopustular rosacea, combination therapy with oral tetracyclines and topical agents is the first–line choice. Treatment with a topical agent, such as metronidazole, may help maintain remission. Patients with ocular involvement ... antibiotics and metronidazole gel. Referral to a subspecialist is necessary for patients who have ocular rosacea with ophthalmic complications, severe or recalcitrant rosacea, or phymatous changes. [more...]

Safety and efficacy of doxycycline in the treatment of rosacea
Clinical, Cosmetic and Investigational Dermatology, 08/13/2009

Valentín S et al. – Rosacea is a common, chronic, skin condition characterized by recurrent episodes of facial flushing, transient or persistent erythema, papules, pustules, and telangiectasias, in a symmetrical facial distribution. Although there is no curative therapy for rosacea ... are oral tetracycline derivatives, including tetracycline, doxycycline, and minocycline. This article reviews the available evidence for the use of doxycycline, a second–generation tetracycline, in the treatment or rosacea. [more...]

Tetracycline Actions Relevant to Rosacea Treatment
Skin Pharmacology and Applied Skin Physiology, 09/30/2009

Korting HC et al. – Tetracycline derivatives like doxycycline successfully used in the treatment of skin diseases like acne and rosacea seem to inhibit different inflammatory pathways involved in the pathogenesis by various modes of action ... are relatively scanty, the following modes of action of tetracyclines seem to be most relevant for an effective treatment of acne and rosacea: inhibition of matrix metalloproteinases, downmodulation of cytokines, inhibition of cell movement and proliferation, inhibition of granuloma formation ... importance. [more...]

Identification of European Allergy Patterns to the Allergen Families PR-10, LTP, and Profilin from Rosaceae Fruits
Clinical Reviews in Allergy and Immunology, 10/27/2009

Andersen MBS et al. – The disease pattern for patients sensitized to profilin is characterized by several concomitant allergies including grass and other pollens, Rosaceae and non–Rosaceae fruits. Finally, PR–10 sensitization ... birch pollen and apple allergy. [more...]

Updates on the Pathophysiology and Management of Acne Rosacea
Postgraduate Medicine, 09/30/2009

Elsaie ML et al. – Recent molecular studies suggest that an altered innate immune response is involved in the pathogenesis of the vascular and inflammatory disease seen in patients with rosacea. These findings may help explain the benefits ... topical treatment agents include metronidazole, azelaic acid, and sodium sulfacetamide–sulfur. Second–line therapies include benzoyl peroxide, clindamycin, calcineurin inhibitors, and permethrin. There are also various systemic therapy options. [more...]

Subjective Disease Perception and Symptoms of Depression in Relation to Healthcare-seeking Behaviour in Patients with Rosacea
Acta Dermato-Venereologica, 09/04/2009

Abram K et al. – Healthcare–seeking behaviour is associated with higher subjective disease perception. The presence of depressive symptoms is not related to severity of the disease, but to the subjective disease perception of rosacea patients. [more...]

A comparison of metronidazole 1% cream and pimecrolimus 1% cream in the treatment of patients with papulopustular rosacea: a randomized open-label clinical trial
Clinical and Experimental Dermatology, 09/23/2009

Koca R et al. – Pimecrolimus cream is no more efficacious than metronidazole cream in the treatment of PR. [more...]

Rosacea: a challenging condition with multiple therapeutic options
Expert Review of Dermatology, 08/20/2009

Sobottka A et al. – Rosacea is one of the most common dermatoses of adults. Topical treatments that are widely accepted are metronidazole and azelaic acid; agents under investigation that may have promising therapeutic ... Systemically, antibiotics, such as tetracyclines and macrolides, and in severe cases isotretinoin, can be used. Surgically, rhinophymas and teleangiectasias can be treated using lasers, dermabrasion or currettage. [more...]

Clinical and cosmeceutical uses of hydroxyacids
Clinics in Dermatology, 08/31/2009

polyhydroxy and bionic acids offer the benefits of alpha–hydroxyacids without irritation, making them suitable for use on sensitive skin, rosacea, and after cosmetic procedures. They also provide additional antioxidant/chelation, barrier strengthening, and moisturizing effects. Bionic acids [more...]

In Vivo Anti-Diabetic Activity of the Ethanolic Crude Extract of Sorbus decora C.K.Schneid. (Rosacea): A Medicinal Plant Used by Canadian James Bay Cree Nations to Treat Symptoms Related to Diabetes
Evidence-based Complementary and Alternative Medicine, 11/05/2009

Vianna R et al. – The ethanol extract of S. decora demonstrates both anti–hyperglycemic [more...]