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Overexpression of metastasis-associated MTA1 in oral squamous cell carcinomas: correlation with metastasis and invasion
International Journal of Oral and Maxillofacial Surgery, 07/23/08
Kawasaki G et al. - In the Matrigel invasion assay, the HSC2 cell line showed the lowest invasion and the OSC20 cell line showed the highest invasion. RNAi-mediated MTA1 silencing in the OSC20 cells decreased the invasion index. MTA1 expression in oral SCC may be associated with increased invasive ability, which may cause lymph node metastasis.
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