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Cytotoxic Effects of Four Different Endodontic Materials in Human Periodontal Ligament Fibroblasts
Journal of Endodontics, 12/12/07
Gorduysus, M., et al. - The purpose of this study was to compare the cytotoxicity, induced apoptosis and/or necrosis, and apoptotic mechanisms in human periodontal ligament (PDL) fibroblasts treated with four different endodontic materials...These results suggest that MTA is a very biocompatible filling material. However, Diaket, Endion, and CYMED 8410 are toxic to PDL fibroblasts in vitro. The main form of cell death induced by these filling materials was determined to be apoptosis and/or necrosis
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