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Baccetti, T., et al. - In this large cross-sectional study, the aim was to analyze growth trends in white subjects with Class III malocclusion using both skeletal and dental maturation staging. Significant changes in total mandibular length occur until young adulthood (18 years on average), with increases between late maturation stages (4 through 6) that were twice as large as in subjects with normal occlusion for the Class III females, and 3 times as large as in subjects with normal occlusion for the Class III males. Growth trends toward accentuated Class III profile and increased vertical dimension of the face also become apparent at late developmental stages

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