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Habersack, K., et al. - This article presents a survey of characteristic features of Williams–Beuren syndrome (WBS) as reported in the literature and the interdisciplinary treatment of a subject with WBS with special regard to morphological and functional disorders. Typical features of a patient with WBS and his dental development in a follow-up from 8 to 25 years of age are shown. Early orthodontic treatment approaches, later combined orthodontic–orthognathic surgical procedures, and the status 5 years after surgery are presented

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