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The Best of 2008
D Scott Cunningham MD, PhD, MDLinx
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Allergy News, General Allergy/Imm Articles Article Summary

Click the title below to leave the MDLinx Network and go to the Journal's Website
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice
Neurobiology of Disease , 11/01/07
Print     Email This Article     Save in My Library   Free Abstract
Clinton, L.K., et al. - We sought to determine if sex impacts the cognitive and neuropathological phenotype of the 3xTg-AD mice. We find that male and female 3xTg-AD mice show comparable impairments on Morris water maze (MWM) and inhibitory avoidance (IA) at 4 months. Shortly thereafter, however, the cognitive performance varies among the sexes, with females performing worse than males

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